Objective: To identify the population-based drug databases in Canada a
nd to determine their comprehensiveness and accessibility for performi
ng pharmacoepidemiologic and outcomes research. Design: Survey (four-p
art mailed questionnaire). Setting: Public and private third-party dru
g plans across Canada. Participants: All provincial and territorial dr
ug plan or pharmacare managers as well as selected private plan manage
rs including health benefit consultants, group insurers and claims adj
udicators/pharmacy benefit managers (CA/PBMs). Outcome measures: Patie
nt, drug and pharmacy information. potential for electronic linkages t
o other provincial databases (e.g., physician, hospital, vital statist
ics); accessibility of information; population profile. Results: Of th
e 32 recipients of the questionnaire 29 (91%) responded and 18 (56%) c
ompleted the survey. Most databases were reported to contain patient i
nformation (e.g., patient identification number, age, sex and medicati
on history) and prescription drug information (e.g., drug identificati
on number, strength, quantity and cost). Six provinces ana one territo
ry reported the capability to link to other databases (e.g., hospital
and physician databases). One CA/PBM reported some links to selected l
ongterm disability data. All of the government databases except those
in British Columbia and the Yukon Territory allowed use of the data fo
r research purposes. Manitoba and Saskatchewan included all residents
of the province in their database; the others included selected groups
(e.g., residents 65 years of age or older, people on social assistanc
e or people covered by private group insurance). Conclusion: A number
of public and private population-based databases are available for use
in pharma-coepidemiologic and outcomes research.