REGIONAL ASSIGNMENT OF HUMAN ESTS BY WHOLE-GENOME RADIATION HYBRID MAPPING

Authors
HAYES PD SCHMITT K JONES HB GYAPAY G WEISSENBACH J GOODFELLOW PN
Citation
Pd. Hayes et al., REGIONAL ASSIGNMENT OF HUMAN ESTS BY WHOLE-GENOME RADIATION HYBRID MAPPING, Mammalian genome, 7(6), 1996, pp. 446-450
Citations number
17
Categorie Soggetti
Biology,"Genetics & Heredity","Biothechnology & Applied Migrobiology
Journal title
Mammalian genome → ACNP
ISSN journal
09388990
Volume
7
Issue
6
Year of publication
1996
Pages
446 - 450
Database
ISI
SICI code
0938-8990(1996)7:6<446:RAOHEB>2.0.ZU;2-Y
Abstract
The UK HGMP Resource Centre's collection of human partial cDNA sequenc es (ESTs) have been examined for suitability for mapping by PCR on a p anel of somatic cell hybrids. The chromosomal assignments of 92 ESTs w ere determined with a monochromosomal hybrid panel, and a subset of 45 were linked to genetic markers with a panel of whole-genome radiation hybrids (WG-RHs). These results demonstrate the potential of WG-RHs t o construct a transcript map of the human genome.