OBJECTIVE: To describe the cytologic features of renal cell carcinoma
(RCC) and renal papillary adenoma in children. STUDY DESIGN: Analysis
of three cases of RCC and one of renal papillary adenoma. RESULTS: Cyt
ologic features of pediatric RCC were essentially the same as those se
en in adults and are characterized by cells with abundant, vacuolated
cytoplasm with pleomorphic nuclei. RCC should be distinguished from th
e more common Wilms' tumor. Cells with abundant, vacuolated cytoplasm
and absence of blastemal cells were two important distinguishing featu
res. A large number of papillae, intranuclear inclusions and magenta b
odies were important cytologic features of renal papillary adenoma. CO
NCLUSION Cytologic features of ACC and adenoma in childhood are charac
teristic, and preoperative diagnosis of these cases is possible by asp
iration cytology.