A 2D SMART PIXEL DETECTOR FOR TIME-RESOLVED PROTEIN CRYSTALLOGRAPHY

Citation
E. Beuville et al., A 2D SMART PIXEL DETECTOR FOR TIME-RESOLVED PROTEIN CRYSTALLOGRAPHY, IEEE transactions on nuclear science, 43(3), 1996, pp. 1243-1247
Citations number
2
Categorie Soggetti
Nuclear Sciences & Tecnology","Engineering, Eletrical & Electronic
ISSN journal
00189499
Volume
43
Issue
3
Year of publication
1996
Part
2
Pages
1243 - 1247
Database
ISI
SICI code
0018-9499(1996)43:3<1243:A2SPDF>2.0.ZU;2-R
Abstract
A smart pixel detector is being developed for Time Resolved Crystallog raphy for biological and material science applications. Using the Pixe l Detector presented here, the Laue method will. enable the study of t he evolution of structural changes that occur within the protein as a function of time. The x-ray pixellated detector is assembled to the in tegrated circuit through a bump bonding process. Within a pixel size o f 150x150 mu m(2), a low noise preamplifier-shaper, a discriminator, a 3 bit counter and the readout logic are integrated The read out, base d on the Column Architecture principle, will accept hit rates above 5x 10(8)/cm(2)/s with a maximum hit rate per pixel of 1MHz. This detector will allow time resolved Laue crystallography to be performed in a fr ameless operation mode, without dead time. Target specifications, arch itecture and preliminary results on the 8x8 front-end prototype and th e column readout are presented.