Impaired hemostasis was studied in 50 adult patients with HIV infectio
n. The blood coagulative potential, the number and functional activity
of platelets were examined. Platelet aggregation and secretion were s
hown to change earlier than thrombocytopenia developed and clinical si
gns of HIV infection appeared. The disturbance in the plasma section o
f hemostasis are due to concurrent opportunistic diseases and infectio
ns.