STUDIES ON ORGANOMETALLIC COMPOUNDS - AN APPROACH TOWARDS CHARACTERIZATION OF STRUCTURE AND ACTIVITY OF TRIORGANOSTANNYL 2-(ARYLAZO)BENZENECARBOXYLATES IN RELATION TO THE BACTERIAL-CELL WALL
Bb. Maji et al., STUDIES ON ORGANOMETALLIC COMPOUNDS - AN APPROACH TOWARDS CHARACTERIZATION OF STRUCTURE AND ACTIVITY OF TRIORGANOSTANNYL 2-(ARYLAZO)BENZENECARBOXYLATES IN RELATION TO THE BACTERIAL-CELL WALL, Proceedings of the Indian Academy of Sciences. Chemical sciences, 105(3), 1993, pp. 183-187
Organostannyl 2-(arylazo)benzenecarboxylates have shown great promise
in inhibiting the growth of Gram-positive bacteria. A possible explana
tion for the structure-activity relationship (SAR) has been discussed
through an intercalation mechanism. The intercalative binding mechanis
m finds support from spectral, chemical as well as X-ray computer mole
cular modelling evidences. An interpretation of the activity against v
arious microorganisms has also been made in the present investigation.