STUDIES ON ORGANOMETALLIC COMPOUNDS - AN APPROACH TOWARDS CHARACTERIZATION OF STRUCTURE AND ACTIVITY OF TRIORGANOSTANNYL 2-(ARYLAZO)BENZENECARBOXYLATES IN RELATION TO THE BACTERIAL-CELL WALL

Authors
MAJI BB PAIN S BISWAS G GHATAK KL GANGULY SN BANERJEE A
Citation
Bb. Maji et al., STUDIES ON ORGANOMETALLIC COMPOUNDS - AN APPROACH TOWARDS CHARACTERIZATION OF STRUCTURE AND ACTIVITY OF TRIORGANOSTANNYL 2-(ARYLAZO)BENZENECARBOXYLATES IN RELATION TO THE BACTERIAL-CELL WALL, Proceedings of the Indian Academy of Sciences. Chemical sciences, 105(3), 1993, pp. 183-187
Citations number
9
Categorie Soggetti
Chemistry
Journal title
Proceedings of the Indian Academy of Sciences. Chemical sciences → ACNP
ISSN journal
02534134
Volume
105
Issue
3
Year of publication
1993
Pages
183 - 187
Database
ISI
SICI code
0253-4134(1993)105:3<183:SOOC-A>2.0.ZU;2-G
Abstract
Organostannyl 2-(arylazo)benzenecarboxylates have shown great promise in inhibiting the growth of Gram-positive bacteria. A possible explana tion for the structure-activity relationship (SAR) has been discussed through an intercalation mechanism. The intercalative binding mechanis m finds support from spectral, chemical as well as X-ray computer mole cular modelling evidences. An interpretation of the activity against v arious microorganisms has also been made in the present investigation.