J. Agut et al., ANTIINFLAMMATORY ACTIVITY OF TOPICALLY APPLIED SERTACONAZOLE NITRATE, Methods and findings in experimental and clinical pharmacology, 18(4), 1996, pp. 233-234
The antiinflammatory activity of topically applied sertaconazole nitra
te was investigated. The dermal administration of 2% sertaconazole con
azole to rats, in which edema was induced by application of croton oil
in the external ear, induced a 39.8% reduction of edema. The results
show that sertaconazole applied by topical route at the concentration
at which it is used in clinic, has antiinflammatory action in this exp
erimental model.