ANTIINFLAMMATORY ACTIVITY OF TOPICALLY APPLIED SERTACONAZOLE NITRATE

Authors
AGUT J TARRIDA N SACRISTAN A ORTIZ JA
Citation
J. Agut et al., ANTIINFLAMMATORY ACTIVITY OF TOPICALLY APPLIED SERTACONAZOLE NITRATE, Methods and findings in experimental and clinical pharmacology, 18(4), 1996, pp. 233-234
Citations number
5
Categorie Soggetti
Pharmacology & Pharmacy
Journal title
Methods and findings in experimental and clinical pharmacology → ACNP
ISSN journal
03790355
Volume
18
Issue
4
Year of publication
1996
Pages
233 - 234
Database
ISI
SICI code
0379-0355(1996)18:4<233:AAOTAS>2.0.ZU;2-3
Abstract
The antiinflammatory activity of topically applied sertaconazole nitra te was investigated. The dermal administration of 2% sertaconazole con azole to rats, in which edema was induced by application of croton oil in the external ear, induced a 39.8% reduction of edema. The results show that sertaconazole applied by topical route at the concentration at which it is used in clinic, has antiinflammatory action in this exp erimental model.