FREQUENCY OF CHROMOSOMAL-ABERRATIONS AFTER EXPOSURE TO GAMMA-RADIATION OF HUMAN CHORIONIC VILLI

Authors
SALVI R DEANDREIS C PARIANI S ORSINI S PIANTANIDA M ROSSELLA F SIMONI G
Citation
R. Salvi et al., FREQUENCY OF CHROMOSOMAL-ABERRATIONS AFTER EXPOSURE TO GAMMA-RADIATION OF HUMAN CHORIONIC VILLI, MUTATION RESEARCH, 291(3), 1993, pp. 213-216
Citations number
8
Categorie Soggetti
Genetics & Heredity",Toxicology
Journal title
MUTATION RESEARCH → ACNP
ISSN journal
00275107
Volume
291
Issue
3
Year of publication
1993
Pages
213 - 216
Database
ISI
SICI code
0027-5107(1993)291:3<213:FOCAET>2.0.ZU;2-8
Abstract
We investigated the chromosomal damage induced by in vitro exposure to gamma-rays of uncultured first trimester chorionic villi. Frequency a nd types of chromosomal aberrations at increasing doses of radiation h ave been evaluated on cytotrophoblast spontaneous metaphases obtained after a short term incubation. Our results indicate a direct correlati on between radiation dose and aberration frequency.