About one third of all patients with systemic sclerosis (SS) presents
colon abnormalities, although these may be underestimated because they
frequently remain asymptomatic for a long time. Thirty-five patients
(33 women and 2 men; mean age 56.5 years; mean disease duration 11.9 y
ears) affected by SS (25 with limited and 10 with diffuse pattern of s
kin involvement) were investigated using barium enema to detect radiol
ogical changes in the colon, and to correlate them with other visceral
involvement, autoantibody profile, abdominal symptoms and duration of
the disease, Ten patients (28.6 %) showed X-rays abnormalities (exclu
ding isolated diverticula), wide-mouthed sacculations being the most f
requent finding, Our data confirm that the colon is frequently involve
d in SS, even in the limited form of the disease, The most relevant fi
nding was the dissociation between clinical symptoms and radiological
features which proved to be more evident among the patients with limit
ed SS, No correlations were found between the radiological picture and
any other parameter, thus suggesting that careful evaluation of the c
olon should be performed in any patient suffering from the disease.