We are reporting a systemic lupus erythematosus patient with antiphosp
holipid syndrome who developed iliofemoral thrombosis. Before the occu
rrence of iliofemoral venous thrombosis, antiphospholipid antibodies (
aPL) gradually decreased over a period of 18 weeks but were, within no
rmal range during its acute phase. In the course of two years followin
g this case of thrombosis, aPL have never returned to the high prethro
mbotic values. It is therefore most likely that aPL were involved in t
he process of provoking thrombosis rather than being consumed during i
ts acute phase.