D. Sapunar et al., EFFECT OF MATERNAL HYPEROXYGENATION ON EXPERIMENTALLY PRODUCED UTEROPLACENTAL INSUFFICIENCY IN THE RAT, Reproduction, fertility and development, 8(3), 1996, pp. 379-381
The paper examines the effects of maternal hyperoxygenation on uteropl
acental insufficiency produced by ligation of the uterine artery. Mate
rnal hyperoxygenation did not significantly affect experimentally prod
uced growth retardation or survival of the fetuses from the ligated ho
rn. Analysis of the vascular anatomy revealed that additional oxygen i
mproves the survival of fetuses compromised by uteroplacental insuffic
iency only in the presence of anastomosis between the uterine and ovar
ian arteries. The study demonstrated the importance of that anastomosi
s in evaluating the results obtained by this experimental model.