CEREBROSPINAL-FLUID PURINE METABOLITES AFTER COMPLEX FEBRILE CONVULSIONS

Adenosine monophosphate, inosine monophosphate, inosine, adenosine, gu anosine, adenine, guanine, hypoxanthine, xanthine and uric acid were d etermined in cerebrospinal fluid (CSF) of 15 children after complex fe brile seizures (CFS) and in 27 after simple febrile seizures (SFS), an d compared with those in a control group of 63 children. There was no statistically significant difference between the groups for any of the se metabolites, suggesting that CFS and SFS neither significantly dist urb the metabolism of nucleotides, nucleosides or bases nor significan tly deplete neuron adenosine triphosphate levels.