A GENERAL-MODEL FOR EXPOSURE AND UPTAKE FROM CONSUMER PRODUCTS

To assess exposure to and uptake of chemical compounds from consumer p roducts, a general model framework is proposed. The model framework se parates exposure into the components contact, potential exposure, and potential uptake rate, and establishes the relation between the three. It adds a contact function and a spatial component to other exposure modeling concepts. Before the model framework can be used, its compone nts need to be specified. A simple diffusional model is built as an ex ample of specifying functions for exposure and uptake. A case study of 1,1,1 trichloroethane in some shoe impregnating product, partly based on the diffusional uptake model, illustrates the inclusion of the con tact component. In the latter example, the exposure is calculated for the user and then, by only modifying the contact component, for a nonu ser randomly walking in the house.