F. Barbe et al., CONTINUOUS POSITIVE AIRWAY PRESSURE IS EFFECTIVE IN TREATING UPPER AIRWAY EDEMA, The European respiratory journal, 9(5), 1996, pp. 1092-1093
The case of a patient with diffuse idiopathic skeletal hyperostosis (D
ISH) and upper airway oedema, is described. The patient presented with
alveolar hypoventilation and obstructive apnoeas during sleep. Intrav
enous steroids (methylprednisolone, 160 mg . day(-1)) for 5 days did n
ot reduce the oedema. However, it was rapidly reversed by the use of n
asal continuous positive airway pressure (nCPAP). In addition, daytime
pulmonary gas exchange was improved and sleep apnoea abolished, This
beneficial effect made tracheostomy unnecessary. This case report sugg
ests that CPAP can be a potentially useful therapeutic alternative to
tracheostomy in the clinical management of upper airway oedema.