OBSTETRIC AND PERINATAL OUTCOME OF PREGNANCIES FOLLOWING INTRACYTOPLASMIC SPERM INJECTION

The aim of this study was to describe the obstetric and perinatal outc ome for births following intracytoplasmic sperm injection (ICSI), Of 2 10 infants born, 140 were singletons and 70 were twins, There were no triplets or higher births, The multiple birth frequency was 20%, Overa ll, 17% of deliveries were preterm, although for singleton pregnancies the incidence was reduced to 9%, The median birth weight of all live born infants was 3168 g and of singletons 3470 g, Of all infants, 17% had a low birth weight (<2500 g) and 2% had a very low birth weight (< 1500 g), Two major malformations occurred in two singleton children an d four minor malformations occurred in four children, This was within the range of expected values in Sweden, Karyotyping was performed in 5 8 pregnancies, All of them were normal, The perinatal mortality was 0. 5%, In conclusion, in this observational study from Sweden of the firs t infants born after ICSI in our programme, the incidence of multiple births, preterm births, low birth weight babies and congenital malform ations was low compared with other series of in-vitro fertilization pr egnancies not associated with ICSI.