BIOTRANSFORMATIONS OF ACYCLIC TERPENOIDS, (+ -)-TRANS-NEROLIDOL AND GERANYLACETONE, BY GLOMERELLA-CINGULATA/

Microbial transformations of (+/-)-trans-nerolidol and geranylacetone were carried out with a plant pathogenic fungus, Glomerella cingulata. (+/-)-trans-Nerolidol and geranylacetone were hydrated at a remote do uble bond as the main metabolic pathway. A large amount of (E)-3,7,11- trimethyl-1,6-dodecadiene-3,11-diol and small amount (E)-3,7,11-trimet hyl-1,6-dodecadiene-3,10,11-triol were obtained from (+/-)-trans-nerol idol. Geranylacetone was transformed to (E)-10-hydroxy-6,10-dimethyl-5 -undecen-2-one as the major metabolite. (E)-9,10-Dihydroxy-6,10-dimeth yl-5-undecen-2-one, (E)-6,10-dimethyl-5,9-undecadien-2-ol, (E)-6,10-di methyl-5-undecene-2,9,10-trio and (E)-6,10-dimethyl-5-undecene-2,10-di ol were also obtained from geranylacetone. The structures of metabolic products were determined by spectroscopic data.