We. Morgan et al., CONGENITAL HETEROTOPIC GASTROINTESTINAL CYST OF THE ORAL CAVITY IN A NEONATE - CASE-REPORT AND REVIEW OF LITERATURE, International journal of pediatric otorhinolaryngology, 36(1), 1996, pp. 69-77
Heterotopic gastrointestinal cysts of the oral cavity are rare benign
lesions which may mimic both benign and malignant neoplasms. These cys
ts are usually discovered during infancy, but may not appear until wel
l into adulthood. This lesion involves the tongue and floor of the mou
th in 97% of cases and has a male predilection. The cyst may range in
size from less than 1 cm to 9 cm, with most lesions being 1-3 cm in si
ze. About 30% of affected individuals have symptoms related to difficu
lties with feeding, swallowing and respiration. The epithelial lining
is quite variable, but all cysts have an enteric lining. The histogene
sis is related to entrapment of undifferentiated, noncommitted endoder
m within the oral cavity during the 3rd-4th week of fetal life. The pu
rpose of this paper is to report a congenital heterotopic gastrointest
inal cyst of the oral cavity presenting in a neonate. The clinical and
histopathologic features of this cyst are reviewed, as well as the hi
stogenesis of this lesion.