Necrotizing fasciitis is a life-threatening soft tissue infection char
acterized by extensive necrosis of the subcutaneous tissues due to pro
gressive bacterial infection and thrombosis of the blood supply. These
patients are usually septic and present both critical care and wound
care challenges, particularly suitable for the Burn Team. We reviewed
our three-year experience, providing care to 45 patients with necrotiz
ing fasciitis. Patients were transferred from an outlying hospital or
from another surgical service for wound and intensive care in the Burn
Unit. The patients were debrided rapidly and repetitively until evide
nce of bacteriologic control was obtained by tissue quantitative cultu
re. Extensive dressing changes with topical antibiotics were accomplis
hed daily with conscious sedation techniques within the Bum Unit, freq
uently using ketamine for analgesia. Attention was particularly given
to adequate nutritional support, splinting, and physical therapy. The
mean patient age was 43.9 years (range 1 to 81), and 58 percent were m
ale. Six patients died for a mortality rate of 13 percent. Necrotizing
fasciitis was caused by drug injection (in 13 patients), trauma (7),
perirectal abscess (4), skin infection (4), meningococcemia (3), intra
abdominal infection (3), Fournier's gangrene (2), infected pressure ul
cer (1), peripheral vascular disease (1), post-operative (1), and idio
pathic (6). Strep was the most common organism, but 58 percent were po
lymicrobial. The mean wound size was 9.8 percent TBSA (range 1 to 30 p
ercent); 16 were truncal, 21 extremity, and 8 perineum. Forty-three pa
tients needed 230 operative debridements total (average 5.35 each), an
d 64 procedures for closure (58 skin grafts, 3 flaps, and 3 primary cl
osures) in 37 patients. Sixty-two percent of the skin-grafted patients
were closed with the first graft (average 1005 cm(2)). One survivor w
as allowed to heal secondarily, and another was returned to his manage
d care facility for closure. The patients required 30.3 days for hospi
talization (range 3 to 102). In this selected group of patients with d
ifficult wounds, burn service expertise produced an excellent survival
rate of 87 percent. In addition, these patients kept the Bum Team bus
y and maintained the intensive care unit census.