PURPOSE: To assess effectiveness of metallic endovascular stents in tr
eatment of venous stenoses and occlusions. MATERIALS AND METHODS: Sten
ts were placed intravenously in 56 patients (59 stenoses or occlusions
) over a 6-year period. Stent sites included the inferior vena cava (n
= 10) and common iliac (n = 31), external iliac (n = 46), common femo
ral (n = 27), and superficial femoral veins (n = 4). Indications for s
tent placement included stenoses from pelvic malignancy and its treatm
ent; trauma, surgery, or pregnancy; and idiopathic stenoses. Patients
underwent anticoagulation therapy for 3-6 months after stent placement
. Follow-up was performed with duplex ultrasound. RESULTS: With use of
life-table analysis, overall primary and secondary 1-year patency rat
es were 50% and 81%, respectively. Primary and secondary 4-year patenc
y rates were and 50% and 75%, respectively. Five patients died of prim
ary disease progression within 6 months after stent placement. Major c
omplications occurred in 6.8% of cases. One-year secondary patency rat
es were statistically significantly lower (P =.05) for patients with m
alignant disease, although primary patency rates were comparable. Over
all sustained decrease in symptoms (P <.0001) was observed 1 year late
r. CONCLUSION: Endovascular stent placement is a nonsurgical alternati
ve for reestablishment of venous now and sustained relief of symptoms
in patients with malignant or benign pelvic venous flow and sustained
relief of symptoms in patients with malignant or benign pelvic venous
disease.