Aims-Analysis of the choroidal findings in patients affected by serpig
inous choroidopathy (SC). Methods-Thirteen patients (23 eyes; 11 males
and two females; age range 50-68 years; mean age 59.1 years) affected
by SC were examined with fluorescein angiography (FA) and indocyanine
green angiography (ICGA), The follow up period was 7-33 months. Resul
ts-Using ICGA the disease could be divided into the the following stag
es: (1) subclinical or choroidal stage (hypofluorescent lesions withou
t FA evidence); (2) active stage (with ICGA and FA evidence); (3) subh
ealing stage (slight late hyperfluorescent lesions with ICGA, with no
evidence on FA); (4) inactive or healed stage (hypofluorescent areas w
ith ICGA and hyperfluorescent areas with FA). Conclusions-Although FA
showed a clear distinction between active and healed stages, ICGA allo
wed a greater subdivision of the disease. In particular, ICGA allowed:
(1) better staging of SC, revealing choroidal alterations when there
was no ophthalmoscopic or FA evidence; (2) better identification of th
e active lesions which appear to be larger at the choroidal level in c
omparison with the corresponding retinal lesions; and (3) revealed a p
ersistence of choroidal activity even when the signs of retinal activi
ty had disappeared. Thus, ICGA should be a particularly useful clinica
l and therapeutic monitoring tool of SC.