MECHANISMS OF OBESITY-INDUCED HYPERTENSION

Authors
HALL JE ZAPPE DH ALONSOGALICIA M GRANGER JP BRANDS MW KASSAB SE
Citation
Je. Hall et al., MECHANISMS OF OBESITY-INDUCED HYPERTENSION, News in physiological sciences, 11, 1996, pp. 255-261
Citations number
15
Categorie Soggetti
Physiology
Journal title
News in physiological sciences → ACNP
ISSN journal
08861714
Volume
11
Year of publication
1996
Pages
255 - 261
Database
ISI
SICI code
0886-1714(1996)11:<255:MOOH>2.0.ZU;2-B
Abstract
Obesity is a major cause of human essential hypertension. Recent studi es point toward increased renal tubular reabsorption and abnormal rena l pressure natriuresis in mediating obesity hypertension. The mechanis ms for these renal changes appear to be multifactorial, including acti vation of the sympathetic nervous system and altered intrarenal histol ogy, which compresses the renal medulla.