ENCAPSULATED ISLET-CELL THERAPY FOR THE TREATMENT OF DIABETES - INTRAPERITONEAL INJECTION OF ISLETS

Authors
Citation
P. Soonshiong, ENCAPSULATED ISLET-CELL THERAPY FOR THE TREATMENT OF DIABETES - INTRAPERITONEAL INJECTION OF ISLETS, Journal of controlled release, 39(2-3), 1996, pp. 399-409
Citations number
30
Categorie Soggetti
Pharmacology & Pharmacy",Chemistry
ISSN journal
01683659
Volume
39
Issue
2-3
Year of publication
1996
Pages
399 - 409
Database
ISI
SICI code
0168-3659(1996)39:2-3<399:EITFTT>2.0.ZU;2-S
Abstract
This report describes the results of the first known report of insulin independence following an intraperitoneal transplantation of encapsul ated islets in a Type I diabetic patient (P. Soon-Shiong, R. Heintz, N . Merideth, X. Yao Qiang, Z. Yao, T. Zheng, M. Murphy, M. Moloney, M. Schmehl, M. Harris, R. Mendez, R. Mendez and P. Sandford, Insulin inde pendence in a Type I diabetic patient after encapsulated islet transpl antation, Lancet 343 (1994) April 16). These findings are encouraging and raise the potential that microencapsulated cell therapy may prove to be a method whereby early-onset diabetes may be treated in the futu re, and the complications of this disease avoided.