Objective: To study the relationship between sleep and nocturnal mictu
rition in women 40-64 years old. Methods: A questionnaire study was ca
rried out in 3669 (6000 invited) randomly selected women in the County
of Jamtland in Sweden. Questions were asked about the general state o
f health, nocturnal micturition, sleep, menstruation and menopausal sy
mptoms, and also about visits to doctors and the use of sleeping pills
and hormone preparations. Results: The subjective evaluation of the g
eneral state of health and of a feeling of contentedness and of confid
ence in the future worsened with increasing numbers of nocturnal voidi
ng episodes. Sleep was more strongly correlated to the number of noctu
rnal voiding episodes (R(2) = 0.099; P < 0.0001) than to age (R(2) = 0
.021; P < 0.0001) or the menopause (R(2) = 0.017; P < 0.0001). Daytime
sleepiness was three times more common among women with three or more
nocturnal voiding episodes than among those with no nocturnal micturi
tion. Women who voided three or more times in the night consulted a do
ctor twice as frequently as those without nocturnal micturition and we
re treated with drugs 2.5 times as often. The corresponding figures fo
r sick-listing were 75 and 15 days per year, respectively. Conclusion:
Frequent nocturnal micturition is common in 40-64-year-old women and
impair sleep with subsequent decrease in daytime performance and gener
al well-being.