G. Fradet et al., IATROGENIC PATHOLOGY IN ELDERLY, INDUCING HOSPITALIZATION - A ONE-YEAR RETROSPECTIVE STUDY IN AN INTERNAL-MEDICINE DEPARTMENT, La Revue de medecine interne, 17(6), 1996, pp. 456-460
Iatrogenic pathology is mainly seen in the elderly. In a one year retr
ospective study, we showed that drug toxicity was responsible for 87 c
ases requiring hospitalisation in patients aged 65 years and above (7.
7% of hospital admission for patients over 65 years). The major manife
stations were: 21 cases of sera electrolyte disturbance, 19 concerning
gastro-intestinal tract and liver, 16 cardiological disorders, 13 neu
rological complications, ten involving the endocrine system, six hemat
ological complications. The most common drugs involved were: antihyper
tensive agents (36%), of which 20.5% were diuretics, psychotherapeutic
drugs (24.8%), anti-inflammatory drugs (17.8%). The average cost per
patient was calculated to 20,602 FF per patient. Impossibility for dir
ect return to the original dwelling place was another complication in
29% of hospitalisations related to iatrogenic disorders. The high numb
er of drugs taken daily increases the risk of drug interactions which
was responsible for iatrogenic accidents in 12.6% of the patients of t
his study.