Ag. Chacko et al., VALUE OF VISUAL-EVOKED POTENTIAL MONITORING DURING TRANS-SPHENOIDAL PITUITARY SURGERY, British journal of neurosurgery, 10(3), 1996, pp. 275-278
The visual outcome of 22 patients undergoing trans-sphenoidal excision
of pituitary macroadenomas with intraoperative flash visual evoked po
tential (VEP) monitoring (Group A), was compared with a non-randomized
group of 14 patients who had undergone similar operations without VEP
monitoring (Group B). Tumour size, preoperative visual acuity, periph
eral fields, and latencies and amplitudes of P1 and P2 were analysed t
o ascertain the best predictor of postoperative visual function. It wa
s found that patients in Group A had a significantly greater improveme
nt in field defects than those in Group B. There was no difference in
postoperative improvement in visual acuity between the two groups. Non
e of the variables analysed were good predictors of visual outcome.