A COMPARATIVE TRIAL USE OF SULPIRIDE AND RISPERIDONE IN HUNTINGTONS-DISEASE - A PILOT-STUDY

Authors
REVELEY MA DURSUN SM ANDREWS H
Citation
Ma. Reveley et al., A COMPARATIVE TRIAL USE OF SULPIRIDE AND RISPERIDONE IN HUNTINGTONS-DISEASE - A PILOT-STUDY, J PSYCHOPH, 10(2), 1996, pp. 162-165
Citations number
13
Categorie Soggetti
Neurosciences,"Pharmacology & Pharmacy","Pharmacology & Pharmacy",Neurosciences,"Clinical Neurology
Journal title
JOURNAL OF PSYCHOPHARMACOLOGY
ISSN journal
02698811 → ACNP
Volume
10
Issue
2
Year of publication
1996
Pages
162 - 165
Database
ISI
SICI code
0269-8811(1996)10:2<162:ACTUOS>2.0.ZU;2-6
Abstract
Sulpiride and risperidone treatment significantly improved the abnorma l involuntary movements of two patients with Huntington's disease on b oth actometer and clinical assessments. However, treatment with risper idone, but not sulpiride, significantly improved the functional activi ties as assessed by the Functional Disability Scale. To the best of ou r knowledge this is the first report of the successful treatment of Hu ntington's disease with risperidone.