The watermelon stomach is a vascular malformation at the gastric antru
m which is responsible for chronic bleeding. We report here nine patie
nts (5 females and 4 males) referred to our Department from December 1
990 to May 1995 with ferropenic anemia resulting from chronic gastroin
testinal bleeding and with the diagnosis of watermelon stomach. The me
an age at presentation was 52 years (range, 29-80). Seven patients req
uired periodic blood transfusions and the remaining patients therapy w
ith iron compound. All patients were treated with photocoagulation of
antral lesions with Nd-YAG laser applied endoscopically. In all patien
ts an almost complete disappearance of endoscopic lesions was achieved
and during the 19-month follow-up period (range, 2-54) no patient req
uired blood transfusions or iron therapy. No secondary complications f
rom therapy were noted.