Objective: To evaluate morbidity, mortality and cure rate after transh
iatal oesophagectomy for carcinoma of the oesophagus. Design: Prospect
ive audit. Setting: University hospital, India. Subjects: From Decembe
r 1986 to June 1993 a total of 250 consecutive patients underwent one
stage transhiatal oesophagectomy with cervical oesophagogastrostomy fo
r carcinoma of the oesophagus. Interventions: Transhiatal oesophagecto
my. Main outcome measures: Morbidity and mortality. Results: The morta
lity was 6% (14/250) and complications included recurrent laryngeal ne
rve palsy (n = 35, 14%), anastomotic leak (n = 38, 15%), respiratory f
ailure (n = 8, 3%), anastomotic stenosis (n = 44, 18%) and anastomotic
recurrence (n = 3, 1%). The actuarial survival at one year was 45% an
d at five years was 5%. Conclusions: Transhiatal oesophagectomy is saf
e and well tolerated for the treatment of carcinoma of the oesophagus
when done with care. Avoidance of thoracotomy, adequate longitudinal c
learance, cervical anastomosis, and a short operating time are its mai
n advantages.