Dt. Mcconnell et al., RISING INCIDENCE OF VULVAR CANCER IN NORTH-EAST SCOTLAND 1974-94 - A POPULATION-BASED STUDY, International journal of gynecological cancer, 6(4), 1996, pp. 309-312
Incidence trends for vulval cancer between 1974 and 1994 within a geog
raphically static population are reported. The age standardized incide
nce rate for combined vulval tumor types is increasing (P = 0.014). A
similar trend for squamous cell carcinoma of the vulva was observed wh
ich may be important, but this did not reach statistical significance.
A subgroup analysis of age at diagnosis, tumor stage, smoking history
and parity for the two time periods 1974-83 and 1984-94 failed to ide
ntify changes which might identify an underlying cause for this rise.
Careful scrutiny of pathology records detected significant cancer regi
stry under-ascertainment. Further population based studies in other ge
ographic areas would be useful to confirm this rise and to examine fur
ther trends in squamous cell carcinoma incidence.