P. Lennox et al., LOCAL-ANESTHESIA IN FLEXIBLE NASENDOSCOPY - A COMPARISON BETWEEN COCAINE AND CO-PHENYLCAINE, Journal of Laryngology and Otology, 110(6), 1996, pp. 540-542
Flexible nasendoscopy is now an integral part of the diagnostic proces
s in Otorhinolaryngology, Topical local anaesthesia is generally recom
mended and cocaine is usually the drug of choice in view of its concur
rent vasoconstrictor action. However, it is expensive. a controlled dr
ug and serious side effects have been reported. Co-phenylcaine forte i
s a new preparation which also has both local anaesthetic and vasocons
trictor properties. This study compares the efficacy of cocaine and Co
-phenylcaine in flexible nasendoscopy and concludes that they provide
similar local anaesthesia and vasoconstriction of the nasal mucosa. Co
-phenylcaine forte can therefore be used as an alternative to cocaine
in flexible nasendoscopy.