The aim of this study is to report a case of cystadenoma in the liver
and to discuss the difficulty of differential diagnosis from malignant
tumor and the importance of complete resection of the lesion. The pat
ient had epigastric pain and abdominal distension. Hepatic ultrasonogr
aphy, abdominal CT, magnetic resonance imaging, and angiography showed
the presence of a large cystic tumor occupying the right hepatic lobe
indicating malignant cystadenocarcinoma. Needle biopsy of the cyst wa
ll with sampling of the cyst fluid was performed, which revealed no ma
lignant cells. However, CEA and CA19-9 were markedly elevated in the c
yst fluid. A right trisegmentectomy via laparotomy was performed succe
ssfully. The resected tumor was 11.5x9x9 cm in size and weighed 1,240
g. The cut surface revealed the tumor with multiple cysts, in some par
ts of which large papillary projections into lumina were seen. Though
the gross features were similar to those of cystadenocarcinoma, the fi
nal histological diagnosis was benign cystadenoma of the liver. The po
stoperative course was uneventful, and the patient is in good conditio
n six years postoperatively without evidence of recurrence of the dise
ase.