Most options for rejuvenation of the lower face use soft-tissue filler
s that augment the appropriate sites. Each of these options has associ
ated risks and benefits. The U.S. Food and Drug Administration recentl
y approved the use of expanded polytetrafluoroethylene (E-PTFE) as a s
oft-tissue filler in the face. From January 1991 through December 1993
, the authors used E-PTFE soft-tissue patches for lower facial augment
ation in 41 patients at 115 implant site. Postsurgical follow-up has r
anged from 2.5 to 4.5 years; during this time, complications have occu
rred in 4 patients. One implant had to be removed because of a seroma
(1 patient), 4 implants required further secondary augmentation (2 pat
ients), and 1 implant required revision because of malposition (1 pati
ent). There have been no cases of implant infection, extrusion, long-t
erm inflammation, or capsule formation. In this article, the authors r
eview the technical aspects of E-PTFE use and discuss issues relating
to the long-term efficacy of this new option for soft-tissue augmentat
ion. The technique is also compared with other options for rejuvenatio
n of the lower face.