BREAST-CANCER TC-99M SM3 RADIOIMMUNOSCINTIGRAPHY

Tc-99m SM3 radioimmunoscintigraphy is combined with kinetic analysis a nd probability mapping using a change detection algorithm to investiga te axillary node involvement before primary surgery in patients with b reast cancer. Whereas planar imaging was unsuccessful, axillary node i nvolvement was correctly determined in 11 out of 13 patients 6 out of 7 true negatives and 5 out of 6 true positives down to 0.35 grams. A p rospective study is underway.