MICRONUCLEUS TEST OF ERYTHROCYTES AND LYMPHOCYTES IN THE BLOOD OF THEPEOPLE LIVING IN THE RADIATION POLLUTION ZONE AS A RESULT OF THE ACCIDENT AT THE SIBERIAN CHEMICAL-PLANT ON APRIL 6, 1993
Nn. Ilyinskikh et al., MICRONUCLEUS TEST OF ERYTHROCYTES AND LYMPHOCYTES IN THE BLOOD OF THEPEOPLE LIVING IN THE RADIATION POLLUTION ZONE AS A RESULT OF THE ACCIDENT AT THE SIBERIAN CHEMICAL-PLANT ON APRIL 6, 1993, Mutation research. Section on environmental mutagenesis and related subjects, 361(2-3), 1996, pp. 173-178
We have carried out analysis of the number of blood erythrocytes and l
ymphocytes with micronuclei in the inhabitants of four settlements loc
ated near the place of the accident which happend at the atomic power
station of the Siberian chemical plant (Tomsk-7) on April 6, 1993. In
all cases, the people examined showed a considerable increase in the n
umber of cells with micronuclei as compared with the control. We obser
ved the same people for 2 years and found a gradual decrease in the nu
mber of cells with micronuclei. This study shows that people born betw
een 1963-1970 have a much higher level of cells with micronuclei, whic
h we tend to see as a result of the radiation accident at the Siberian
chemical plant in 1963. The data we have obtained allow us to conclud
e that penetration of radionuclides into the human organism in the pre
natal and early postnatal periods can lead to the formation of stable
clones of erythroid cells with micronuclei and a higher level of eryth
rocytes with micronuclei which can remain in the blood for a long time
.