Objective: Rheumatic fever has become infrequent in developed countrie
s, Recent regional epidemics, particularly in North America, brought o
ur attention to this disease in our area, In the French Caribbean Isla
nds, rheumatic fever remains an important health problem despite much
progress in the last 15 years, Methods: A retrospective survey over th
e last 5 years identified 19 cases of rheumatic fever in Guadeloupe in
subjects over 19 years of age, Results: Among these subjects 4 cases
of rheumatic fever beginning in adulthood were analysed and compared w
ith data in the literature, Conclusion: The diagnosis of rheumatic fev
er beginning in adulthood is difficult to establish, Joint symptoms ar
e variable and cardiac involvement, which occurs in 30 to 40% of the c
ases, is highly suggestive, The kinetics of antistreptococci antibodie
s confirms the diagnosis.