STRUCTURE OF SANGUINARINE BASE

Authors
DOSTAL J BOCHORAKOVA H TABORSKA E SLAVIK J POTACEK M BUDESINSKY M DEHOFFMANN E
Citation
J. Dostal et al., STRUCTURE OF SANGUINARINE BASE, Journal of natural products, 59(6), 1996, pp. 599-602
Citations number
21
Categorie Soggetti
Chemistry,"Plant Sciences","Pharmacology & Pharmacy
Journal title
Journal of natural products → ACNP
ISSN journal
01633864
Volume
59
Issue
6
Year of publication
1996
Pages
599 - 602
Database
ISI
SICI code
0163-3864(1996)59:6<599:SOSB>2.0.ZU;2-H
Abstract
The structure of sanguinarine free base was examined. The base is eith er bis[6-(5,6-dihydrosanguinarinyl)] ether (3) or bis[6-(5,6-dihydrosa nguinarinyl)]amine (4) depending on whether Na2CO3 or NH3, respectivel y, is used as an alkalizing agent. Oxysanguinarine (5) was identified as a side product formed by disproportionation of the pseudobase inter mediate 2a.