Introgenic necrosis of the pituitary gland is well-known but rarely ca
used by stimulation tests used to investigate pituitary adenomas; 26 c
ases have been reported in the Literature. We report 2 new cases where
the chronology of the events suggests the sudden necrosis resulted fr
om stimulation tests, Several mechanisms have been proposed, It is not
possible to define increased risk as a function of the adenoma histol
ogy, In most cases, voluminous tumors are revealed by visual dysfuncti
on. These accidents should not overshadow the role of function tests i
n neurosurgical situations, Outcome is usually favorable after acute n
ecrosis.