Purpose: To determine whether the use of low-viscosity intermediate re
sins (LVR) reduces microleakage of dental adhesive systems. Materials
and Methods: Wedge-shaped Class V cavities were prepared in sound extr
acted molars. Occlusal margins were in enamel and gingival margins wer
e in dentin/cementum. Five adhesive systems (All-Bond 2, Clearfil Line
r Bond 2, OptiBond, Prime & Bond and Scotchbond Multi-Purpose) were ap
plied to the preparations strictly according to manufacturers' directi
ons on one side of the tooth and with the addition of LVR (OptiBond FL
Adhesive or Protect Liner F) on the other. All cavities were restored
with Z100 resin composite. Specimens were then stored in water at 37
degrees C for 24 hours, thermocycled 800x, stained with silver nitrate
, sectioned, and evaluated for leakage. Marginal penetration of silver
nitrate was scored on 0-3 scale. Results: Statistical analysis (Krusk
al-Wallis non-parametric ANOVA) revealed a significant difference (P<
0.0001) in leakage at dentin margins. Multiple pairwise comparisons of
control groups revealed considerable overlapping between groups, but
with a trend toward less leakage by OptiBond and Clearfil Liner Bond 2
. Leakage of Scotchbond Multi-Purpose was significantly reduced when P
rotect Liner F was used.