ADDITION OF ORGANOLITHIUM REAGENTS TO ALPHA-(TRIFLUOROMETHYL)STYRENE - CONCISE SYNTHESIS OF FUNCTIONALIZED GEM-DIFLUOROALKENES

Authors
BEGUE JP BONNETDELPON D ROCK MH
Citation
Jp. Begue et al., ADDITION OF ORGANOLITHIUM REAGENTS TO ALPHA-(TRIFLUOROMETHYL)STYRENE - CONCISE SYNTHESIS OF FUNCTIONALIZED GEM-DIFLUOROALKENES, Journal of the Chemical Society. Perkin transactions. I, (12), 1996, pp. 1409-1413
Citations number
32
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of the Chemical Society. Perkin transactions. I → ACNP
ISSN journal
0300922X
Issue
12
Year of publication
1996
Pages
1409 - 1413
Database
ISI
SICI code
0300-922X(1996):12<1409:AOORTA>2.0.ZU;2-W
Abstract
The treatment of alpha-(trifluoromethyl)styrene with organolithium rea gents results in the selective formation of gem-difluoroalkenes in goo d-to-excellent yields. This reaction has been applied to the synthesis of 3-gem-difluoro-2-phenylallylic amines and other functionalised gem -difluoroalkenes.