DIASTEREOSELECTIVITY OF CHLORIDE SUBSTITUTION-REACTIONS OF CYCLORUTHENATED (R)(C)-(- AND (S)(C)-(-)-DIMETHYL(1-PHENYLETHYL)AMINE())

The diastereoselectivity of chloride substitution in the two enantiome ric ruthenacycles (S-Ru, R(C))- and (R(Ru), S-C)-{(eta(6)-C6H6)RU(C6H4 CH(Me)N(Me)(2)]}} by bromide, iodide, and selected nitrogen and phosph orus donor ligands has been determined by a combination of H-1, C-13- {H-1}, and P-31{H-1} NMR spectroscopy, UV-visible spectroscopy, circul ar dichroism, and, where possible, single-crystal X-ray crystallograph y. The diastereoselectivity generally increases with increasing steric bulk of the incoming ligand and proceeds with predominant retention o f configuration at ruthenium.