REACTION OF INDOLES WITH ELECTRON-DEFICIENT OLEFINS CATALYZED BY YB(OTF)(3)CENTER-DOT-3H(2)O

Authors
HARRINGTON PE KERR MA
Citation
Pe. Harrington et Ma. Kerr, REACTION OF INDOLES WITH ELECTRON-DEFICIENT OLEFINS CATALYZED BY YB(OTF)(3)CENTER-DOT-3H(2)O, Synlett, (11), 1996, pp. 1047
Citations number
20
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synlett → ACNP
ISSN journal
09365214
Issue
11
Year of publication
1996
Database
ISI
SICI code
0936-5214(1996):11<1047:ROIWEO>2.0.ZU;2-I
Abstract
Treatment of indoles with a variety of electron deficient olefins unde r the influence of Yb(OTf)(3)3H(2)O leads to alkylation of the indoles at the 3-position in moderate to excellent yields. This mild coupling procedure may offer a convenient entry into the hapalindole class of marine alkaloids.