Jp. Baker et Ra. Siegel, HYSTERESIS IN THE GLUCOSE PERMEABILITY VERSUS PH CHARACTERISTIC FOR ARESPONSIVE HYDROGEL MEMBRANE, Macromolecular rapid communications, 17(6), 1996, pp. 409-415
A side-by-side diffusion cell was used to study the permeability of gl
ucose through a temperature- and pH-sensitive poly(N-isopropylacrylami
de-co-methacrylic acid) hydrogel membrane. At fixed temperature (37 de
grees C), lowering pH in one side of the cell induced hydrogel volume
collapse and strongly attenuated glucose permeation across the membran
e. Hysteresis was observed in the glucose permeability versus pH chara
cteristic.