The global minimization of an indefinite quadratic function over a bou
nded polyhedral set using a decomposition branch and bound approach is
considered. The objective function consists of an unseparated convex
part and a separated concave part. The large-scale problems are charac
terized by having the number of convex variables much more than that o
f concave variables. The advantages of the the method is that it uses
the rectangular subdivision on the subspace of concave variables. Usin
g a easily constructed convex underestimating function to the objectiv
e function, a lower bound is obtained by solving a convex quadratic pr
ogramming problem. Three variants using exhaustive, adaptive and w-sub
division are discussed. Computational results are presented for proble
ms with 10-20 concave variables and up to 200 convex variables.