U. Baldari et al., CHRONIC BULLOUS DISEASE OF CHILDHOOD FOLLOWING EPSTEIN-BARR-VIRUS SEROCONVERSION - A CASE-REPORT, Clinical and experimental dermatology, 21(2), 1996, pp. 123-126
We report the case of a 3-year-old boy with classical chronic bullous
disease of childhood (CBDC) arising after recent Epstein-Barr virus se
roconversion following infectious mononucleosis. The patient also had
small red cells and decreased levels of circulating IgA. He received c
ombined treatment with dapsone and prednisone with good results. Our r
eport is the first of CBDC preceded by Epstein-Barr virus seroconversi
on. The virus may have had an initial immunopathogenic role in the gen
esis of the bullous eruption.