The use of calixarenes in sensing devices represents an area of rapid
advances over the past 10 years. Calixarenes are ideal candidates as s
ensor materials, providing platforms or templates to which can be atta
ched subunits capable of performing particular sensing roles. Polar gr
oups with predetermined properties can be used for guest recognition,
chromophores, fluorophores or electroactive groups for transduction of
host-guest interaction, and groups which facilitate immobilisation on
a substrate surface or within a polymer chain or membrane.