ISOLATION AND SEQUENCING OF THE CDNA-ENCODING PHOSPHATIDYLINOSITOL TRANSFER PROTEIN FROM RABBIT LUNG

Authors
TSAO FHC CHENG W CHEN XR HU JP CHEN XM
Citation
Fhc. Tsao et al., ISOLATION AND SEQUENCING OF THE CDNA-ENCODING PHOSPHATIDYLINOSITOL TRANSFER PROTEIN FROM RABBIT LUNG, Gene, 172(2), 1996, pp. 299-302
Citations number
22
Categorie Soggetti
Genetics & Heredity
Journal title
Gene → ACNP
ISSN journal
03781119
Volume
172
Issue
2
Year of publication
1996
Pages
299 - 302
Database
ISI
SICI code
0378-1119(1996)172:2<299:IASOTC>2.0.ZU;2-E
Abstract
The cDNA clones encoding rabbit lung phosphatidylinositol transfer pro tein (PI-TP) were isolated and sequenced. The putative polypeptide con sisted of 270 amino acid (aa) residues, the same as human PI-TP, but o ne aa residue less than the PI-TP of rat and mouse. PI-TP RNA expressi on in various tissues of a pregnant rabbit was analyzed by Northern bl ot. Brain, placenta and fallopian tube had the highest PI-TP RNA expre ssion. PI-TP RNA expression in alveolar epithelial type-II cells isola ted from rabbit lung markedly increased after a 24-h culture, suggesti ng that PI-TP RNA expression in type-II cells can be modified by ambie nt factors.