ELECTROPHILIC SUBSTITUTION-REACTIONS OF [1]BENZOTHIENO[3,2-B]FURAN

Authors
SVOBODA J PIHERA P SEDMERA P PALECEK J
Citation
J. Svoboda et al., ELECTROPHILIC SUBSTITUTION-REACTIONS OF [1]BENZOTHIENO[3,2-B]FURAN, Collection of Czechoslovak Chemical Communications, 61(6), 1996, pp. 888-900
Citations number
36
Categorie Soggetti
Chemistry
Journal title
Collection of Czechoslovak Chemical Communications → ACNP
ISSN journal
00100765
Volume
61
Issue
6
Year of publication
1996
Pages
888 - 900
Database
ISI
SICI code
0010-0765(1996)61:6<888:ESO[>2.0.ZU;2-E
Abstract
In chlorination, bromination, iodination, nitration, sulfonation, form ylation, and trifluoroacetylation of [1]benzothieno[3,2-b]furan (1) th e substituent enters the 2-position. The said halogenations go by the addition-elimination mechanism. When the substitution is continued, th e second substituent enters the 6-position of heterocycle 1. The H-1 a nd C-13 NMR spectra have been completely assigned. Substituent effects on NMR parameters are discussed.