SHORT-TERM CADMIUM INTOXICATION OF THE SHRIMP PALAEMON SERRATUS - EFFECT ON ADENYLATE METABOLISM

Citation
Mt. Thebault et al., SHORT-TERM CADMIUM INTOXICATION OF THE SHRIMP PALAEMON SERRATUS - EFFECT ON ADENYLATE METABOLISM, Comparative biochemistry and physiology. Part C, Pharmacology toxicology & endocrinology, 113(3), 1996, pp. 345-348
Citations number
25
Categorie Soggetti
Biology,"Pharmacology & Pharmacy",Toxicology
ISSN journal
13678280
Volume
113
Issue
3
Year of publication
1996
Pages
345 - 348
Database
ISI
SICI code
1367-8280(1996)113:3<345:SCIOTS>2.0.ZU;2-7
Abstract
1. Shrimps were exposed for 96 hr to various concentrations of cadmium under laboratory conditions. The LC(50) was around 4 ppm Cd in water, which corresponded to 0.180 mu g/g wet weight of cadmium in tail musc les. 2. The effect of various concentrations of cadmium on adenylates was analyzed in tail muscles: At subletal cadmium concentrations, no v ariation of ATP, ADP and of the adenylate sum occurred, while the AMP concentration began to decrease from 0.06 ppm.At the LC(50) the ATP, A DP and AMP concentrations dropped acutely, the ATP/ADP ratio increased acutely. The apparent equilibrium constant of the adenylate kinase re action increased significantly from 2 ppm Cd, indicating an impairment in energetic metabolism. Cadmium intoxication did not influence the v alue of the adenylate energy charge.