INFORMED CHOICE IN FRAGILE-X SYNDROME AND ITS EFFECTS ON PREVALENCE

Authors
ROBINSON H WAKE S WRIGHT F LAING S TURNER G
Citation
H. Robinson et al., INFORMED CHOICE IN FRAGILE-X SYNDROME AND ITS EFFECTS ON PREVALENCE, American journal of medical genetics, 64(1), 1996, pp. 198-202
Citations number
11
Categorie Soggetti
Genetics & Heredity
Journal title
American journal of medical genetics → ACNP
ISSN journal
01487299
Volume
64
Issue
1
Year of publication
1996
Pages
198 - 202
Database
ISI
SICI code
0148-7299(1996)64:1<198:ICIFSA>2.0.ZU;2-J
Abstract
We present the effect of case finding, cascade testing, and counsellin g for fragile X syndrome in a population of 6.5 million over a decade, Carrier females made informed choices that resulted in a 10-fold decr ease in the prevalence of affected males ill their off-spring. (C) 199 6 Wiley-Liss, Inc.