Recently, Witten has proposed a mechanism for symmetry enhancement in
SO(32) heterotic string theory, where the singularity obtained by shri
nking an instanton to zero size is resolved by the appearance of an Sp
(1) gauge symmetry. In this short letter, we consider spacetime constr
aints from anomaly cancellation in six dimensions and D-flatness and d
emonstrate a subtlety which arises in the moduli space when many insta
ntons are shrunk to zero size.